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Normal Database Creation

The concept of the normal database assumes that the perfusion and the metabolism of the myocardium in a healthy left ventricle shows a consistent pattern. It furthermore assumes that the segmentation model is a suitable standardization of the anatomy across persons. Under these premises, the results obtained with healthy hearts can be pooled for a statistical analysis to establish the average and the normal variation in each segment. This information represents the normal database for a certain type of cardiac scans. Results found in a patient scan can then be compared against this database resulting in an absolute deviation from the normal value per segment which can also be expressed as a fraction of the standard deviation (z-score).

The principle steps for building a normal database are:

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