2-Compartment Model

The FDG model is a standard 2-tissue compartment model with two additional input parameters, the lumped constant (LC) and the plasma glucose concentration (PG). In combination with the estimated K₁, k₂, and k₃ parameters they allow to calculate the metabolic rate of glucose.

Note: In the FDG model k₄ is initially set to 0 assuming metabolic trapping, but can also be fitted.