Neurology: PALZ Case 2 | PALZ Case 1 | PALZ Case 3 | PXMOD Case

History

• 74-year old male.
• Based on clinical symptoms suspicion of vascular dementia, Alzheimer's Disease, or both.
  
• Patient is referred for PET scan to examine for Alzheimer's Disease by Memory Clinic, Königsfelden, Switzerland.

Visual Inspection

• The FDG PET images indicates an uptake pattern concordant with Alzheimer's Disease.

FDG images. Click on the image for viewing more transaxial slices.

PALZ Findings

• The analysis reveals a clear bilateral hypometabolism within the parietal, frontal and temporal cortex as well as posterior cingulate gyrus
  
• Criterion within AD regions is abnormal with high error probabilitiy (t-Sum=44531.34; p<0.0001).

Cluster images of significant hypometabolism. Click on the image for viewing more transaxial images.

3D Visualization

Diagnosis

• According to the PALZ result and in accordance with the clinical symptoms Alzheimer's Disease is diagnosed.
• A vascular component of the disease can not be excluded based on PET.