| 2011-12-15 | Build 3 of Version 3.3 available for Download |
| Build 3 of version 3.3 is ready for download. See release notes for details.
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| 2011-12-01 | Build 8 of Version 3.2 available for Download |
| Build 8 of version 3.2 is ready for download. See release notes for details.
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| 2011-10-30 | New Product Release 3.3 |
| Version 3.3 is ready for download. See release notes for details.
Selection of the major highlights:
- Reorganization of the fusion tool interface, particularly of the initialization part of matching.
- Support for plasma fraction functions in the kinetic modeling tool, as well as area-under-the-curve (AUC) calculations. Dedicated model configurations can be saved with user-defined names.
- Extension of VOI features: automatic brain VOI generation, region-growing methods in 2D and 3D, VOI intersection calculation, VOI erosion and dilation, contour interpolation.
- PMOD real-time aquisition tool (PSAMPLE) for devices such as the twilite swisstrace blood sampler.
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| 2011-10-26 | 5th Annual Renewal of Maintenance Agreement with Genentech, Inc. |
| Two groups at Genentech, Inc., a member of the Roche Group, are longstanding users of PMOD. The company has renewed their "Maintenance Agreement for PMOD Software" for a fifth consecutive annual period. |
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| 2011-09-27 | Twilite Blood Sampling Device (Swisstrace) |
| The gold standard of PET quantification is kinetic modeling using information about the tracer concentration in arterial blood.
To promote wider use of PET quantification Swisstrace has introduced
a new online blood sampling device for humans and animals. It is highly sensitive and accurate due to coincidence counting with
LYSO crystals, and the unique design makes it fully MR compatible.
PMOD is proud to provide the PSAMPLE data acquisition software for this sophisticated instrument. |
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| 2011-08-03 | New Criterion to Predict Progression from MCI to AD |
| A new study by Herholz et al (J Nucl Med August 1, 2011 vol. 52, 1218-1226) introduces a new "PET Score" criterion derived from FDG brain PET scans.
It is shown to be a valid imaging biomarker for monitoring the progression of mild cognitive impairment (MCI) to Alzheimer's disease (AD).
Its superior test-retest reliability and signal strength will allow the reduction in the number of subjects needed in clinical trials or shortening of study duration substantially.
The PET score can be easily calculated from the analysis of FDG brain images with PMOD's current Alzheimer's tool (PALZ).
The next version to the tool available in Oct. 2011 will yield the "PET Score" as an additional result. |
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| 2010-10-28 | New Product Release 3.2 |
| Version 3.2 is ready for download. See release notes for details.
Selection of the major highlights:
- Complete work-flow oriented revision of the PXMOD tool. Additionally, the image fusion tool is directly integrated into PXMOD to support the pixel-oriented comparison of parametric maps.
- Support for various automated partial-volume correction (PVC) methods. The VOI-based approach implements Rousset's GTM method. The VOIs can be manually outlined or automatically derived from standard VOI templates. A brain MRI based approach implements the method proposed by Muller-Gartner. It includes the required PET-MR matching as well as the MRI segmentation without the need for any user interaction.
- Ability to calculate and apply the inverse of all transforms (rigid and elastic) calculated in the fusion tool. Furthermore, VOIs can now also be transformed, not only images. Together, these new features allow easily transferring template VOIs to the patient images for performing the template-based statistics on the original PET images.
- A new version (ATL) was developed which supports all the features required for CFR part 11 compliant data analyses. It is mainly intended for CROs and includes full audit trails, data protection and advanced reporting.
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| 2010-08-18 | Build 7 of Version 3.1 available for Download |
| Build 7 of version 3.1 is ready for download. See release notes for details.
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| 2010-04-01 | Maintenance Agreement with RIKEN, Kobe, Japan |
| The RIKEN institution located in Kobe, Japan, comprises a prominent Molecular Imaging Research Program. RIKEN's imaging group and PMOD have signed a maintenance agreement to further strengthen their longstanding collaboration. |
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| 2010-01-30 | Performance Assessment of PALZ Tool |
| Haense et al. have tested the performance of the PALZ tool with data from two different databases.
The study confirms the high accuracy of FDG PET with PALZ for the discrimination between Alzheimer's Dementia patients and normal controls.
Furthermore it demonstrates that PALZ can be equally applied to studies with eyes open or closed during the uptake phase.
Only 7 out of 464 images had to be excluded from the analysis due to a failure of the normalization procedure. |
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| 2009-10-26 | New Product Release 3.1 |
| The new 3.1 product version is now available. It incorporates more than 130 improvements with main highlights in VOI and kinetic modeling functionalities, as documented in the Release Notes.
Selection of some notable improvements:
- Flexible inclusion/exclusion functionality on the contour and VOI level to create complex VOIs from which inner parts are spared.
- Usage of indvidual pixels to form VOIs or to extend existing VOIs; exclusion of pixels from existing VOIs.
- Combination of masks with VOIs, for example to restrict contour VOIs to gray matter segments.
- Introduction of geometric VOI objects which can be scaled and moved in all directions.
- Randomized fitting of kinetic models with randomly generated initial parameters for avoiding local minima.
- Automatic initial parameter determination for compartment models by the linear least squares method.
- User-defined parameter defaults per kinetic model.
- Extended history of the tested kinetic models which allows to easily compare their outcome.
- Improved user interface for more easily producing nice Volume Renderings in the 3D tool.
CAUTION: As a consequence of the improvements, kinetic modeling in the 3.1 version may return slightly different results than the prior versions. Please refer to the Release Notes for details.
All users with purchased base version 3.0 are encouraged to freely download and use this significantly improved PMOD version.
During the installation you will be able to import the configuration of your prior installation. In this way your working environment
will be easily migrated. Note that your old license file will work with version 3.1.
All other users need to purchase an upgrade for using the 3.1 version.
Note: Builds of the current PMOD version are prepared at irregular intervals, mainly for fixing bugs. We strongly recommend using the latest build of a version. |
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| 2009-10-22 | DopaSoft: Clinical Software Development for IBA Molecular |
| PMOD has developed a diagnostic software package called DopaSoft for the analysis of FDOPA PET scans. This package will be rolled out in the Bordeaux area by IBA in the first quarter of 2010. |
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| 2008-11-22 | Site License for Karolinska Institute, Sweden |
| The research group at the Karolinska Institutet PET Centre is a large-scale user of PMODīs kinetic modeling and image fusion solutions.
In order to consolidate and further advance the usage of the PMOD software, a site license agreement has been signed.
Opinion of Prof. Christer Halldin and Dr. Andrea Varrone: "PMOD is a very useful and versatile tool for image and data analysis in PET research,
providing a variety of solutions for optimal quantification of neuroreceptor PET studies." |
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| 2008-10-31 | Product Release 3.0 |
| The new 3.0 product version is now available. It includes numerous improvements and new features, as documented in the release notes.
Some of the notable changes are
- VOI: Undo function for contour VOIs.
- VOI: Outlining supported in all plane directions (alos in coronal and sagittal).
- VOI: Revised user interface which offers more image space.
- PKIN: Metabolite correction models are included.
- Database/DICOM Server: are now included in the base license.
- PXMOD: New models and masking functionality added.
- PFUS: Taskbar with hotkeys for frequent tasks added.
All users with purchased base version 2.9 or 2.95 are encouraged to freely download and use this improved release.
Note that your old license file will work. |
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| 2008-01-12 | Clinical Evaluation of the Alzheimer's Discrimination Tool |
| The IRCCS Centro San Giovanni di Dio of Brescia is the Italian national centre for research and care of Alzheimer's and mental diseases. The IRCSS will assess the value of the PALZ tool in the workout of preclinical Alzheimer's disease. |
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| 2007-12-01 | New Office located in Zurich |
| PMOD Technologies has opened a new office in the center of Zurich, Switzerland. |
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| 2007-11-05 | Reselling Agreement for Taiwan and China |
| PMOD Technologies has signed an agreement with Cold Spring Biotech Corp, Taipei. As of Nov. 5, 2007,
Cold Spring Biotech Corp has the exclusive rights for distributing the PMOD software in Taiwan and China. |
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| 2007-07-08 | Reselling Agreement for Japan |
| PMOD Technologies has signed an agreement with PET Technology Supplies, Tokyo, Japan. As of July 1, 2007,
PET Technology Supplies has the exclusive rights for distributing the PMOD software in Japan. |
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| 2007-02-01 | OEM Agreement with Gamma Medica-Ideas |
| PMOD Technologies has signed an agreement with Gamma Medica-Ideas, Northridge, CA, U.S.A. Gamma Medica-Ideas will offer PMOD as an option with their suite of animal scanners for advanced post processing. |
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| 2006-12-22 | OEM Agreement with GEM-Imaging |
| PMOD Technologies has signed an agreement with General Equipment for Medical Imaging, Paterna (Valencia), Spain. GEM-Imaging will offer PMOD as an option with their new animal PET scanner for advanced post processing. |
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| 2006-09-28 | OEM Agreement with MILabs |
| PMOD Technologies has signed an agreement with Molecular Imaging Laboratories, Utrecht, The Netherlands. MILabs will offer PMOD as an option with their new, high-resolution animal U-SPECT scanner for advanced post processing. |
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| 2005-11-10 | Collaboration with University of Ottawa Heart Institute |
| PMOD Technologies and Dr. deKemp from the Ottawa Heart Institute have started a collaboration to improve the cardiac quantification within PMOD. The main focus is on streamlining the application for routine usage with Ammonia and Rubidium, and on extending the range of validated models further. |
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| 2004-12-08 | Reselling Agreement for Korea |
| PMOD Technologies has signed an agreement with New Korea Industrial Co., Ltd, Seoul, Korea. As of Dec. 1, 2004,
New Korea has the exclusive rights for distributing the PMOD software in Korea. |
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| 2004-05-18 | Agreement with Max-Planck-Institute Cologne |
| The Max-Planck-Institute (MPI) Cologne and PMOD Technologies have signed a research contract on May 18, 2004.
PMOD Technologies is entitled to transform the automatic Alzheimer discrimination methodology developed by Dr. Herholz from MPI into a new analysis tool.
Dr. Herholz’ methodology is based on the data of 110 normal FDG scans and has been tested with the data of 395 patients, as documented in
NeuroImage 17, 302-316 (2002).
The new PMOD tool will make an automated evaluation available to the public which has the potential for widespread clinical use to support diagnosis of dementia at a very early stage. |
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| 2003-09-18 | Transferal of Rights to PMOD Technologies Ltd |
| The exclusive rights for the PMOD software are transfered
from the University of Zurich to PMOD Technologies. |
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| 2003-08-21 | Establishment of PMOD Technologies Ltd |
| PMOD Technologies is established
as a spin-off company of the University of Zurich, Switzerland. |
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