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Selected Publications using PMOD for their Data Analysis
2008
  1. Arakawa R, Okumura M, Ito H, Seki C, Takahashi H, Takano H, Nakao R, Suzuki K, Okubo Y, Halldin C, Suhara T. Quantitative Analysis of Norepinephrine Transporter in the Human Brain Using PET with (S,S)-18F-FMeNER-D2. J Nucl Med. 2008;49(8):1270-1276.
  2. Boecker H, Henriksen G, Sprenger T, Miederer I, Willoch F, Valet M, Berthele A, Tolle TR. Positron emission tomography ligand activation studies in the sports sciences: measuring neurochemistry in vivo. Methods. 2008;45(4):307-18.
  3. Boy C, Meyer PT, Kircheis G, Holschbach MH, Herzog H, Elmenhorst D, Kaiser HJ, Coenen HH, Haussinger D, Zilles K, Bauer A. Cerebral A(1) adenosine receptors (A(1)AR) in liver cirrhosis. Eur J Nucl Med Mol Imaging. 2008;35(3):589-97.
  4. Christian N, Lee JA, Bol A, De Bast M, Gallez B, Gregoire V. Immobilization device for in vivo and in vitro multimodality image registration of rodent tumors. Radiother Oncol. 2008;87(1):147-51.
  5. Cropley VL, Fujita M, Bara-Jimenez W, Brown AK, Zhang XY, Sangare J, Herscovitch P, Pike VW, Hallett M, Nathan PJ, Innis RB. Pre- and post-synaptic dopamine imaging and its relation with frontostriatal cognitive function in Parkinson disease: PET studies with [11C]NNC 112 and [18F]FDOPA. Psychiatry Res. 2008;163(2):171-82.
  6. Drzezga A, Grimmer T, Henriksen G, Stangier I, Perneczky R, Diehl-Schmid J, Mathis CA, Klunk WE, Price J, Dekosky S, Wester HJ, Schwaiger M, Kurz A. Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease. Neuroimage. 2008;39(2):619-33.
  7. Frokjaer VG, Pinborg LH, Madsen J, de Nijs R, Svarer C, Wagner A, Knudsen GM. Evaluation of the Serotonin Transporter Ligand 123I-ADAM for SPECT Studies on Humans. J Nucl Med. 2008;49(2):247-54.
  8. Fujita M, Imaizumi M, Zoghbi SS, Fujimura Y, Farris AG, Suhara T, Hong J, Pike VW, Innis RB. Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation. Neuroimage. 2008;40(1):43-52.
  9. Gerstl F, Windischberger C, Mitterhauser M, Wadsak W, Holik A, Kletter K, Moser E, Kasper S, Lanzenberger R. Multimodal imaging of human early visual cortex by combining functional and molecular measurements with fMRI and PET. Neuroimage. 2008;41(2):204-11.
  10. Goffin K, Bormans G, Casteels C, Bosier B, Lambert DM, Grachev ID, Van Paesschen W, Van Laere K. An in vivo [(18)F]MK-9470 microPET study of type 1 cannabinoid receptor binding in Wistar rats after chronic administration of valproate and levetiracetam. Neuropharmacology. 2008;54(7):1103-6.
  11. Herzog H, Elmenhorst D, Winz O, Bauer A. Biodistribution and radiation dosimetry of the A(1) adenosine receptor ligand (18)F-CPFPX determined from human whole-body PET. Eur J Nucl Med Mol Imaging. 2008;35(8):1499-506.
  12. Hooker JM, Xu Y, Schiffer W, Shea C, Carter P, Fowler JS. Pharmacokinetics of the potent hallucinogen, salvinorin A in primates parallels the rapid onset and short duration of effects in humans. Neuroimage. 2008;41(3):1044-50.
  13. Ichise M, Cohen RM, Carson RE. Noninvasive estimation of normalized distribution volume: application to the muscarinic-2 ligand [(18)F]FP-TZTP. J Cereb Blood Flow Metab. 2008;28(2):420-30.
  14. Imaizumi M, Briard E, Zoghbi SS, Gourley JP, Hong J, Fujimura Y, Pike VW, Innis RB, Fujita M. Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors. Neuroimage. 2008;39(3):1289-98.
  15. Jentzen W, Weise R, Kupferschlager J, Freudenberg L, Brandau W, Bares R, Burchert W, Bockisch A. Iodine-124 PET dosimetry in differentiated thyroid cancer: recovery coefficient in 2D and 3D modes for PET(/CT) systems. Eur J Nucl Med Mol Imaging. 2008;35(3):611-23.
  16. Kimes AS, Chefer SI, Matochik JA, Contoreggi CS, Vaupel DB, Stein EA, Mukhin AG. Quantification of nicotinic acetylcholine receptors in the human brain with PET: Bolus plus infusion administration of 2-[(18)F]F-A85380. Neuroimage. 2008;39(2):717-27.
  17. Lodge MA, Jacene HA, Pili R, Wahl RL. Reproducibility of Tumor Blood Flow Quantification with 15O-Water PET. J Nucl Med. 2008;49(10):1620-1627.
  18. Mazere J, Prunier C, Barret O, Guyot M, Hommet C, Guilloteau D, Dartigues JF, Auriacombe S, Fabrigoule C, Allard M. In vivo SPECT imaging of vesicular acetylcholine transporter using [(123)I]-IBVM in early Alzheimer's disease. Neuroimage. 2008;40(1):280-8.
  19. Meyer PT, Sattler B, Winz OH, Fundke R, Oehlwein C, Kendziorra K, Hesse S, Schaefer WM, Sabri O. Kinetic analyses of [(123)I]IBZM SPECT for quantification of striatal dopamine D2 receptor binding: A critical evaluation of the single-scan approach. Neuroimage. 2008;42(2):548-58.
  20. Meyer PT, Circiumaru V, Cardi CA, Thomas DH, Bal H, Acton PD. Simplified quantification of small animal [18F]FDG PET studies using a standard arterial input function. Eur J Nucl Med Mol Imaging. 2006;33(8):948-54.
  21. Millet P, Moulin M, Bartoli A, Del Guerra A, Ginovart N, Lemoucheux L, Buono S, Fagret D, Charnay Y, Ibanez V. In vivo quantification of 5-HT(1A)-[(18)F]MPPF interactions in rats using the YAP-(S)PET scanner and a beta-microprobe. Neuroimage. 2008;41(3):823-34.
  22. Mukhin AG, Kimes AS, Chefer SI, Matochik JA, Contoreggi CS, Horti AG, Vaupel DB, Pavlova O, Stein EA. Greater Nicotinic Acetylcholine Receptor Density in Smokers Than in Nonsmokers: A PET Study with 2-18F-FA-85380. J Nucl Med. 2008;49(10):1628-1635.
  23. Patel VD, Lee DE, Alexoff DL, Dewey SL, Schiffer WK. Imaging dopamine release with Positron Emission Tomography (PET) and (11)C-raclopride in freely moving animals. Neuroimage. 2008;41(3):1051-66.
  24. Pierson ME, Andersson J, Nyberg S, McCarthy DJ, Finnema SJ, Varnas K, Takano A, Karlsson P, Gulyas B, Medd AM, Lee CM, Powell ME, Heys JR, Potts W, Seneca N, Mrzljak L, Farde L, Halldin C. [(11)C]AZ10419369: A selective 5-HT(1B) receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain. Neuroimage. 2008;41(3):1075-85.
  25. Rommel D, Abarca-Quinones J, Christian N, Peeters F, Lonneux M, Labar D, Bol A, Gregoire V, Duprez T. Alginate moulding: an empirical method for magnetic resonance imaging/positron emission tomography co-registration in a tumor rat model. Nucl Med Biol. 2008;35(5):571-7.
  26. Shih YY, Chiang YC, Chen JC, Huang CH, Chen YY, Liu RS, Chang C, Jaw FS. Brain nociceptive imaging in rats using (18)f-fluorodeoxyglucose small-animal positron emission tomography. Neuroscience. 2008;155(4):1221-6.
  27. Shidahara M, Ikoma Y, Seki C, Fujimura Y, Naganawa M, Ito H, Suhara T, Kanno I, Kimura Y. Wavelet denoising for voxel-based compartmental analysis of peripheral benzodiazepine receptors with (18)F-FEDAA1106. Eur J Nucl Med Mol Imaging. 2008;35(2):416-23.
  28. Siegrist PT, Comte N, Holzmeister J, Sutsch G, Koepfli P, Namdar M, Duru F, Brunckhorst C, Scharf C, Kaufmann PA. Effects of AV delay programming on ventricular resynchronisation: role of radionuclide ventriculography. Eur J Nucl Med Mol Imaging. 2008;35(8):1516-22.
  29. Siegrist PT, Husmann L, Knabenhans M, Gaemperli O, Valenta I, Hoefflinghaus T, Scheffel H, Stolzmann P, Alkadhi H, Kaufmann PA. (13)N-ammonia myocardial perfusion imaging with a PET/CT scanner: impact on clinical decision making and cost-effectiveness. Eur J Nucl Med Mol Imaging. 2008;35(5):889-95.
  30. Sprague DR, Fujita M, Ryu YH, Liow JS, Pike VW, Innis RB. Whole-body biodistribution and radiation dosimetry in monkeys and humans of the phosphodiesterase 4 radioligand [(11)C](R)-rolipram: comparison of two-dimensional planar, bisected and quadrisected image analyses. Nucl Med Biol. 2008;35(4):493-500.
  31. Strauss LG, Koczan D, Klippel S, Pan L, Cheng C, Willis S, Haberkorn U, Dimitrakopoulou-Strauss A. Impact of Angiogenesis-Related Gene Expression on the Tracer Kinetics of 18F-FDG in Colorectal Tumors. J Nucl Med. 2008;49(8):1238-1244.
  32. Terry G, Liow JS, Chernet E, Zoghbi SS, Phebus L, Felder CC, Tauscher J, Schaus JM, Pike VW, Halldin C, Innis RB. Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB(1) receptors in rodents. Neuroimage. 2008;41(3):690-8.
  33. Van Laere K, Goffin K, Casteels C, Dupont P, Mortelmans L, de Hoon J, Bormans G. Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET. Neuroimage. 2008;39(4):1533-41.
  34. Van Laere K, Koole M, Sanabria Bohorquez SM, Goffin K, Guenther I, Belanger MJ, Cote J, Rothenberg P, De Lepeleire I, Grachev ID, Hargreaves RJ, Bormans G, Burns HD. Whole-body biodistribution and radiation dosimetry of the human cannabinoid type-1 receptor ligand 18F-MK-9470 in healthy subjects. J Nucl Med. 2008;49(3):439-45.
  35. Van Laere K, Bormans G, Sanabria-Bohorquez SM, de Groot T, Dupont P, De Lepeleire I, de Hoon J, Mortelmans L, Hargreaves RJ, Atack JR, Burns HD. In vivo characterization and dynamic receptor occupancy imaging of TPA023B, an alpha 2/alpha 3/alpha 5 subtype selective gamma-aminobutyric acid-a partial agonist. Biol Psychiatry. 2008;64(2):153-61.
  36. von Forstner C, Egberts JH, Ammerpohl O, Niedzielska D, Buchert R, Mikecz P, Schumacher U, Peldschus K, Adam G, Pilarsky C, Grutzmann R, Kalthoff H, Henze E, Brenner W. Gene Expression Patterns and Tumor Uptake of 18F-FDG, 18F-FLT, and 18F-FEC in PET/MRI of an Orthotopic Mouse Xenotransplantation Model of Pancreatic Cancer. J Nucl Med. 2008;49(8):1362-1370.
  37. Wullner U, Gundisch D, Herzog H, Minnerop M, Joe A, Warnecke M, Jessen F, Schutz C, Reinhardt M, Eschner W, Klockgether T, Schmaljohann J. Smoking upregulates alpha4beta2* nicotinic acetylcholine receptors in the human brain. Neurosci Lett. 2008;430(1):34-7.
  38. Zoghbi SS, Liow JS, Yasuno F, Hong J, Tuan E, Lazarova N, Gladding RL, Pike VW, Innis RB. 11C-loperamide and its N-desmethyl radiometabolite are avid substrates for brain permeability-glycoprotein efflux. J Nucl Med. 2008;49(4):649-56.
2007
  1. Adachi I, Gaemperli O, Valenta I, Schepis T, Siegrist PT, Treyer V, Burger C, Morita K, Kaufmann PA. Assessment of myocardial perfusion by dynamic O-15-labeled water PET imaging: validation of a new fast factor analysis. J Nucl Cardiol. 2007;14(5):698-705.
  2. Ametamey SM, Treyer V, Streffer J, Wyss MT, Schmidt M, Blagoev M, Hintermann S, Auberson Y, Gasparini F, Fischer UC, Buck A. Human PET Studies of Metabotropic Glutamate Receptor Subtype 5 with 11C-ABP688. J Nucl Med. 2007;48(2):247-252.
  3. Boutin H, Chauveau F, Thominiaux C, Gregoire MC, James ML, Trebossen R, Hantraye P, Dolle F, Tavitian B, Kassiou M. 11C-DPA-713: A Novel Peripheral Benzodiazepine Receptor PET Ligand for In Vivo Imaging of Neuroinflammation. J Nucl Med. 2007;48(4):573-581.
  4. Brown AK, Fujita M, Fujimura Y, Liow JS, Stabin M, Ryu YH, Imaizumi M, Hong J, Pike VW, Innis RB. Radiation Dosimetry and Biodistribution in Monkey and Man of 11C-PBR28: A PET Radioligand to Image Inflammation. J Nucl Med. 2007;48(12):2072-2079.
  5. Dimitrakopoulou-Strauss A, Hohenberger P, Haberkorn U, Macke HR, Eisenhut M, Strauss LG. 68Ga-labeled bombesin studies in patients with gastrointestinal stromal tumors: comparison with 18F-FDG. J Nucl Med. 2007;48(8):1245-50.
  6. Doyle B, Kemp BJ, Chareonthaitawee P, Reed C, Schmeckpeper J, Sorajja P, Russell S, Araoz P, Riederer SJ, Caplice NM. Dynamic tracking during intracoronary injection of 18F-FDG-labeled progenitor cell therapy for acute myocardial infarction. J Nucl Med. 2007;48(10):1708-14.
  7. Elmenhorst D, Meyer PT, Matusch A, Winz OH, Zilles K, Bauer A. Test-retest stability of cerebral A1 adenosine receptor quantification using [18F]CPFPX and PET. Eur J Nucl Med Mol Imaging. 2007;34(7):1061-70.
  8. Frumberg DB, Fernando MS, Lee DE, Biegon A, Schiffer WK. Metabolic and behavioral deficits following a routine surgical procedure in rats. Brain Res. 2007;1144:209-18.
  9. Ginovart N, Willeit M, Rusjan P, Graff A, Bloomfield PM, Houle S, Kapur S, Wilson AA. Positron emission tomography quantification of [(11)C]-(+)-PHNO binding in the human brain. J Cereb Blood Flow Metab. 2007;27(4):857-871.
  10. Haberkorn U, Hoffend J, Schmidt K, Altmann A, Bonaterra GA, Dimitrakopoulou-Strauss A, Strauss LG, Eisenhut M, Kinscherf R. Changes in glucose metabolism and gene expression after transfer of anti-angiogenic genes in rat hepatoma. Eur J Nucl Med Mol Imaging. 2007.
  11. Honer M, Stoffel A, Kessler LJ, Schubiger PA, Ametamey SM. Radiolabeling and in vitro and in vivo evaluation of [(18)F]-FE-DABP688 as a PET radioligand for the metabotropic glutamate receptor subtype 5. Nucl Med Biol. 2007;34(8):973-80.
  12. Imaizumi M, Kim HJ, Zoghbi SS, Briard E, Hong J, Musachio JL, Ruetzler C, Chuang DM, Pike VW, Innis RB, Fujita M. PET imaging with [(11)C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat. Neurosci Lett. 2007;411(3):200-5.
  13. Jentzen W, Freudenberg L, Eising EG, Heinze M, Brandau W, Bockisch A. Segmentation of PET Volumes by Iterative Image Thresholding. J Nucl Med. 2007;48(1):108-14.
  14. Kim SW, Ding YS, Alexoff D, Patel V, Logan J, Lin KS, Shea C, Muench L, Xu Y, Carter P, King P, Constanzo JR, Ciaccio JA, Fowler JS. Synthesis and positron emission tomography studies of C-11-labeled isotopomers and metabolites of GTS-21, a partial alpha7 nicotinic cholinergic agonist drug. Nucl Med Biol. 2007;34(5):541-51.
  15. Lanzenberger RR, Mitterhauser M, Spindelegger C, Wadsak W, Klein N, Mien LK, Holik A, Attarbaschi T, Mossaheb N, Sacher J, Geiss-Granadia T, Kletter K, Kasper S, Tauscher J. Reduced serotonin-1A receptor binding in social anxiety disorder. Biol Psychiatry. 2007;61(9):1081-9.
  16. Lauwers E, Beque D, Van Laere K, Nuyts J, Bormans G, Mortelmans L, Casteels C, Vercammen L, Bockstael O, Nuttin B, Debyser Z, Baekelandt V. Non-invasive imaging of neuropathology in a rat model of alpha-synuclein overexpression. Neurobiol Aging. 2007;28(2):248-57.
  17. Le Foll B, Chefer SI, Kimes AS, Shumway D, Goldberg SR, Stein EA, Mukhin AG. Validation of an extracerebral reference region approach for the quantification of brain nicotinic acetylcholine receptors in squirrel monkeys with PET and 2-18F-fluoro-A-85380. J Nucl Med. 2007;48(9):1492-500.
  18. Leroy C, Comtat C, Trebossen R, Syrota A, Martinot JL, Ribeiro MJ. Assessment of 11C-PE2I Binding to the Neuronal Dopamine Transporter in Humans with the High-Spatial-Resolution PET Scanner HRRT. J Nucl Med. 2007;48(4):538-46.
  19. Love Z, Wang F, Dennis J, Awadallah A, Salem N, Lin Y, Weisenberger A, Majewski S, Gerson S, Lee Z. Imaging of mesenchymal stem cell transplant by bioluminescence and PET. J Nucl Med. 2007;48(12):2011-20.
  20. Maeda J, Higuchi M, Inaji M, Ji B, Haneda E, Okauchi T, Zhang MR, Suzuki K, Suhara T. Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor. Brain Res. 2007;1157:100-11.
  21. Mather SJ, McKenzie AJ, Sosabowski JK, Morris TM, Ellison D, Watson SA. Selection of radiolabeled gastrin analogs for Peptide receptor-targeted radionuclide therapy. J Nucl Med. 2007;48(4):615-22.
  22. Matusch A, Hurlemann R, Rota Kops E, Winz OH, Elmenhorst D, Herzog H, Zilles K, Bauer A. Acute S-ketamine application does not alter cerebral [18F]altanserin binding: a pilot PET study in humans. J Neural Transm. 2007;114(11):1433-42.
  23. Meyer PT, Elmenhorst D, Boy C, Winz O, Matusch A, Zilles K, Bauer A. Effect of aging on cerebral A1 adenosine receptors: A [18F]CPFPX PET study in humans. Neurobiol Aging. 2007;28(12):1914-24.
  24. Mirrione MM, Schiffer WK, Fowler JS, Alexoff DL, Dewey SL, Tsirka SE. A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator. Neuroimage. 2007;38(1):34-42.
  25. Mitterhauser M, Toegel S, Wadsak W, Lanzenberger RR, Mien LK, Kuntner C,Wanek T, Eidherr H, Ettlinger DE, Viernstein H, Kluger R, Dudczak R,Kletter K. Pre vivo, ex vivo and in vivo evaluations of [(68)Ga]-EDTMP. Nucl Med Biol. 2007;34(4):391-397.
  26. Miyata J, Hirao K, Namiki C, Fukuyama H, Okada T, Miki Y, Hayashi T, Murai T. Interfrontal commissural abnormality in schizophrenia: tractography-assisted callosal parcellation. Schizophr Res. 2007;97(1-3):236-41.
  27. Oishi N, Hashikawa K, Yoshida H, Ishizu K, Ueda M, Kawashima H, Saji H, Fukuyama H. Quantification of nicotinic acetylcholine receptors in Parkinson's disease with (123)I-5IA SPECT. J Neurol Sci. 2007;256(1-2):52-60.
  28. Penuelas I, Aranguren XL, Abizanda G, Marti-Climent JM, Uriz M, Ecay M, Collantes M, Quincoces G, Richter JA, Prosper F. (13)N-ammonia PET as a measurement of hindlimb perfusion in a mouse model of peripheral artery occlusive disease. J Nucl Med. 2007;48(7):1216-23.
  29. Praschak-Rieder N, Kennedy J, Wilson AA, Hussey D, Boovariwala A, Willeit M, Ginovart N, Tharmalingam S, Masellis M, Houle S, Meyer JH. Novel 5-HTTLPR allele associates with higher serotonin transporter binding in putamen: a [(11)C] DASB positron emission tomography study. Biol Psychiatry. 2007;62(4):327-31.
  30. Ryu YH, Liow JS, Zoghbi S, Fujita M, Collins J, Tipre D, Sangare J, Hong J, Pike VW, Innis RB. Disulfiram inhibits defluorination of (18)F-FCWAY, reduces bone radioactivity, and enhances visualization of radioligand binding to serotonin 5-HT1A receptors in human brain. J Nucl Med. 2007;48(7):1154-61.
  31. Seneca N, Cai L, Liow JS, Zoghbi SS, Gladding RL, Hong J, Pike VW, Innis RB. Brain and whole-body imaging in nonhuman primates with [11C]MeS-IMPY, a candidate radioligand for beta-amyloid plaques. Nucl Med Biol. 2007;34(6):681-9.
  32. Schepis T, Gaemperli O, Treyer V, Valenta I, Burger C, Koepfli P, Namdar M, Adachi I, Alkadhi H, Kaufmann PA. Absolute quantification of myocardial blood flow with 13N-ammonia and 3-dimensional PET. J Nucl Med. 2007;48(11):1783-9.
  33. Schiffer WK, Mirrione MM, Dewey SL. Optimizing Experimental Protocols for Quantitative Behavioral Imaging with 18F-FDG in Rodents. J Nucl Med. 2007;48(2):277-87.
  34. Shetty HU, Zoghbi SS, Liow JS, Ichise M, Hong J, Musachio JL, Halldin C, Seidel J, Innis RB, Pike VW. Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [(11)C]PE2I. Eur J Nucl Med Mol Imaging. 2007;34(5):667-78.
  35. Sprague DR, Chin FT, Liow JS, Fujita M, Burns HD, Hargreaves R, Stubbs JB, Pike VW, Innis RB, Mozley PD. Human Biodistribution and Radiation Dosimetry of the Tachykinin NK1 Antagonist Radioligand [18F]SPA-RQ: Comparison of Thin-Slice, Bisected, and 2-Dimensional Planar Image Analysis. J Nucl Med. 2007;48(1):100-7.
  36. Strobel K, Burger C, Schneider P, Weber M, Hany TF. MIBG-SPECT/CT-angiography with 3-D reconstruction of an extra-adrenal phaeochromocytoma with dissection of an aortic aneurysm. Eur J Nucl Med Mol Imaging. 2007;34(1):150.
  37. Takano A, Arakawa R, Hayashi M, Takahashi H, Ito H, Suhara T. Relationship between neuroticism personality trait and serotonin transporter binding. Biol Psychiatry. 2007;62(6):588-92.
  38. Thanos PK, Michaelides M, Benveniste H, Wang GJ, Volkow ND. Effects of chronic oral methylphenidate on cocaine self-administration and striatal dopamine D2 receptors in rodents. Pharmacol Biochem Behav. 2007;87(4):426-33.
  39. Treyer V, Streffer J, Wyss MT, Bettio A, Ametamey SM, Fischer U, Schmidt M, Gasparini F, Hock C, Buck A. Evaluation of the metabotropic glutamate receptor subtype 5 using PET and 11C-ABP688: assessment of methods. J Nucl Med. 2007;48(7):1207-15.
  40. Vaupel DB, Stein EA, Mukhin AG. Quantification of alpha4beta2* nicotinic receptors in the rat brain with microPET(R) and 2-[(18)F]F-A-85380. Neuroimage. 2007;34:1352-1362.
  41. Wagenknecht G. Acontour tracing and coding algorithm for generating 2D contour codes from 3D classified objects. Pattern Recognition 40 (2007) 1294 - 1306.
  42. Wyss MT, Ametamey SM, Treyer V, Bettio A, Blagoev M, Kessler LJ, Burger C, Weber B, Schmidt M, Gasparini F, Buck A. Quantitative evaluation of (11)C-ABP688 as PET ligand for the measurement of the metabotropic glutamate receptor subtype 5 using autoradiographic studies and a beta-scintillator. Neuroimage. 2007;35(3):1086-92.
  43. Wyss MT, Spaeth N, Biollaz G, Pahnke J, Alessi P, Trachsel E, Treyer V, Weber B, Neri D, Buck A. Uptake of 18F-Fluorocholine, 18F-FET, and 18F-FDG in C6 Gliomas and Correlation with 131I-SIP(L19), a Marker of Angiogenesis. J Nucl Med. 2007;48(4):608-614.
  44. Yoshiyama Y, Higuchi M, Zhang B, Huang SM, Iwata N, Saido TC, Maeda J, Suhara T, Trojanowski JQ, Lee VM. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron. 2007;53(3):337-51.
  45. Zappe AC, Reichold J, Burger C, Weber B, Buck A, Pfeuffer J, Logothetis NK. Quantification of cerebral blood flow in nonhuman primates using arterial spin labeling and a two-compartment model. Magn Reson Imaging. 2007;25(6):775-83.
  46. Zhang MR, Kumata K, Maeda J, Yanamoto K, Hatori A, Okada M, Higuchi M, Obayashi S, Suhara T, Suzuki K. 11C-AC-5216: a novel PET ligand for peripheral benzodiazepine receptors in the primate brain. J Nucl Med. 2007;48(11):1853-61.
2006
  1. Ametamey SM, Kessler LJ, Honer M, Wyss MT, Buck A, Hintermann S, Auberson YP, Gasparini F, Schubiger PA. Radiosynthesis and Preclinical Evaluation of 11C-ABP688 as a Probe for Imaging the Metabotropic Glutamate Receptor Subtype 5. J Nucl Med. 2006;47(4):698-705.
  2. Araya R, Noguchi T, Yuhki M, Kitamura N, Higuchi M, Saido TC, Seki K, Itohara S, Kawano M, Tanemura K, Takashima A, Yamada K, Kondoh Y, Kanno I, Wess J, Yamada M. Loss of M(5) muscarinic acetylcholine receptors leads to cerebrovascular and neuronal abnormalities and cognitive deficits in mice. Neurobiol Dis. 2006;24(2):334-44.
  3. Bauer M, Langer O, Dal-Bianco P, Karch R, Brunner M, Abrahim A, Lanzenberger R, Hofmann A, Joukhadar C, Carminati P, Ghirardi O, Piovesan P, Forloni G, Corrado ME, Lods N, Dudczak R, Auff E, Kletter K, Muller M. A positron emission tomography microdosing study with a potential antiamyloid drug in healthy volunteers and patients with Alzheimer's disease. Clin Pharmacol Ther. 2006;80(3):216-27.
  4. Berding G, Schneider U, Gielow P, Buchert R, Donnerstag F, Brandau W, Knapp WH, Emrich HM, Muller-Vahl K. Feasibility of central cannabinoid CB(1) receptor imaging with [(124)I]AM281 PET demonstrated in a schizophrenic patient. Psychiatry Res. 2006;147(2-3):249-56.
  5. Bettio A, Honer M, Muller C, Bruhlmeier M, Muller U, Schibli R, Groehn V, Schubiger AP, Ametamey SM. Synthesis and Preclinical Evaluation of a Folic Acid Derivative Labeled with 18F for PET Imaging of Folate Receptor-Positive Tumors. J Nucl Med. 2006;47(7):1153-1160.
  6. Casteels C, Vermaelen P, Nuyts J, Van Der Linden A, Baekelandt V, Mortelmans L, Bormans G, Van Laere K. Construction and evaluation of multitracer small-animal PET probabilistic atlases for voxel-based functional mapping of the rat brain. J Nucl Med. 2006;47(11):1858-66.
  7. Cannon DM, Ichise M, Fromm SJ, Nugent AC, Rollis D, Gandhi SK, Klaver JM, Charney DS, Manji HK, Drevets WC. Serotonin transporter binding in bipolar disorder assessed using [11C]DASB and positron emission tomography. Biol Psychiatry. 2006;60(3):207-17.
  8. Chareonthaitawee P, Christenson SD, Anderson JL, Kemp BJ, Hodge DO, Ritman EL, Gibbons RJ. Reproducibility of Measurements of Regional Myocardial Blood Flow in a Model of Coronary Artery Disease: Comparison of H215O and 13NH3 PET Techniques. J Nucl Med. 2006;47(7):1193-1201.
  9. Cropley VL, Fujita M, Musachio JL, Hong J, Ghose S, Sangare J, Nathan PJ, Pike VW, Innis RB. Whole-Body Biodistribution and Estimation of Radiation-Absorbed Doses of the Dopamine D1 Receptor Radioligand 11C-NNC 112 in Humans. J Nucl Med. 2006;47(1):100-4.
  10. Dimitrakopoulou-Strauss A, Georgoulias V, Eisenhut M, Herth F, Koukouraki S, Macke HR, Haberkorn U, Strauss LG. Quantitative assessment of SSTR2 expression in patients with non-small cell lung cancer using(68)Ga-DOTATOC PET and comparison with (18)F-FDG PET. Eur J Nucl Med Mol Imaging. 2006;33(7):823-30.
  11. Fujimura Y, Ikoma Y, Yasuno F, Suhara T, Ota M, Matsumoto R, Nozaki S, Takano A, Kosaka J, Zhang MR, Nakao R, Suzuki K, Kato N, Ito H. Quantitative Analyses of 18F-FEDAA1106 Binding to Peripheral Benzodiazepine Receptors in Living Human Brain. J Nucl Med. 2006;47(1):43-50.
  12. Fujita M, Ichise M, Zoghbi SS, Liow JS, Ghose S, Vines DC, Sangare J, Lu JQ, Cropley VL, Iida H, Kim KM, Cohen RM, Bara-Jimenez W, Ravina B, Innis RB. Widespread decrease of nicotinic acetylcholine receptors in Parkinson's disease. Ann Neurol. 2006;59(1):174-7.
  13. Honer M, Hengerer B, Blagoev M, Hintermann S, Waldmeier P, Schubiger PA, Ametamey SM. Comparison of [18F]FDOPA, [18F]FMT and [18F]FECNT for imaging dopaminergic neurotransmission in mice. Nucl Med Biol. 2006;33(5):607-14.
  14. Ikoma Y, Yasuno F, Ito H, Suhara T, Ota M, Toyama H, Fujimura Y, Takano A, Maeda J, Zhang MR, Nakao R, Suzuki K. Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [(11)C]DAA1106. J Cereb Blood Flow Metab. 2006.
  15. Ikoma Y, Takano A, Ito H, Kusuhara H, Sugiyama Y, Arakawa R, Fukumura T, Nakao R, Suzuki K, Suhara T. Quantitative analysis of 11C-verapamil transfer at the human blood-brain barrier for evaluation of P-glycoprotein function. J Nucl Med. 2006;47(9):1531-7.
  16. Kim JS, Ichise M, Sangare J, Innis RB. PET Imaging of Serotonin Transporters with [11C]DASB: Test-Retest Reproducibility Using a Multilinear Reference Tissue Parametric Imaging Method. J Nucl Med. 2006;47(2):208-214.
  17. Knoch D, Treyer V, Regard M, Muri RM, Buck A, Weber B. Lateralized and frequency-dependent effects of prefrontal rTMS on regional cerebral blood flow. Neuroimage. 2006;31(2):641-8.
  18. Koukouraki S, Strauss LG, Georgoulias V, Eisenhut M, Haberkorn U, Dimitrakopoulou-Strauss A. Comparison of the pharmacokinetics of (68)Ga-DOTATOC and [ (18)F]FDG in patients with metastatic neuroendocrine tumours scheduled for (90)Y-DOTATOC therapy. Eur J Nucl Med Mol Imaging. 2006;33(10):1115-22.
  19. Kunz P, Hoffend J, Altmann A, Dimitrakopoulou-Strauss A, Koczan D, Eisenhut M, Bonaterra GA, Dengler TJ, Mier W, Haberkorn U, Kinscherf R. Angiopoietin-2 overexpression in morris hepatoma results in increased tumor perfusion and induction of critical angiogenesis-promoting genes. J Nucl Med. 2006;47(9):1515-24.
  20. Lin KJ, Liu CY, Wey SP, Hsiao IT, Wu J, Fu YK, Yen TC. Brain SPECT imaging and whole-body biodistribution with [(123)I]ADAM - a serotonin transporter radiotracer in healthy human subjects. Nucl Med Biol. 2006;33(2):193-202.
  21. Matusch A, Meyer PT, Bier D, Holschbach MH, Woitalla D, Elmenhorst D, Winz OH, Zilles K, Bauer A. Metabolism of the A(1) adenosine receptor PET ligand [(18)F]CPFPX by CYP1A2: implications for bolus/infusion PET studies. Nucl Med Biol. 2006;33(7):891-8.
  22. Meyer PT, Elmenhorst D, Matusch A, Winz O, Zilles K, Bauer A. 18F-CPFPX PET: On the Generation of Parametric Images and the Effect of Scan Duration. J Nucl Med. 2006;47(2):200-7.
  23. Meyer PT, Elmenhorst D, Matusch A, Winz O, Zilles K, Bauer A. A1 adenosine receptor PET using [18F]CPFPX: displacement studies in humans. Neuroimage. 2006;32(3):1100-5.
  24. Mirrione MM, Schiffer WK, Siddiq M, Dewey SL, Tsirka SE. PET imaging of glucose metabolism in a mouse model of temporal lobe epilepsy. Synapse. 2006;59(2):119-21.
  25. Muzi M, Spence AM, O'Sullivan F, Mankoff DA, Wells JM, Grierson JR, Link JM, Krohn KA. Kinetic analysis of 3'-deoxy-3'-18F-fluorothymidine in patients with gliomas. J Nucl Med. 2006;47(10):1612-21.
  26. Namdar M, Koepfli P, Grathwohl R, Siegrist PT, Klainguti M, Schepis T, Delaloye R, Wyss CA, Fleischmann SP, Gaemperli O, Kaufmann PA. Caffeine decreases exercise-induced myocardial flow reserve. J Am Coll Cardiol. 2006;47(2):405-10.
  27. Rusjan P, Mamo D, Ginovart N, Hussey D, Vitcu I, Yasuno F, Tetsuya S, Houle S, Kapur S. An automated method for the extraction of regional data from PET images. Psychiatry Res. 2006;147(1):79-89.
  28. Schiffer WK, Volkow ND, Fowler JS, Alexoff DL, Logan J, Dewey SL. Therapeutic doses of amphetamine or methylphenidate differentially increase synaptic and extracellular dopamine. Synapse. 2006;59(4):243-51.
  29. Schiffer WK, Mirrione MM, Biegon A, Alexoff DL, Patel V, Dewey SL. Serial microPET measures of the metabolic reaction to a microdialysis probe implant. J Neurosci Methods. 2006;155(2):272-84.
  30. Schmidt K, Hoffend J, Altmann A, Strauss LG, Dimitrakopoulou-Strauss A, Engelhardt B, Koczan D, Peter J, Dengler TJ, Mier W, Eisenhut M, Haberkorn U, Kinscherf R. Angiostatin Overexpression in Morris Hepatoma Results in Decreased Tumor Growth but Increased Perfusion and Vascularization. J Nucl Med. 2006;47(3):543-551.
  31. Schmidt K, Hoffend J, Altmann A, Kiessling F, Strauss L, Koczan D, Mier W, Eisenhut M, Kinscherf R, Haberkorn U. Troponin I overexpression inhibits tumor growth, perfusion, and vascularization of morris hepatoma. J Nucl Med. 2006;47(9):1506-14.
  32. Siegrist PT, Gaemperli O, Koepfli P, Schepis T, Namdar M, Valenta I, Aiello F, Fleischmann S, Alkadhi H, Kaufmann PA. Repeatability of cold pressor test-induced flow increase assessed with H(2)(15)O and PET. J Nucl Med. 2006;47(9):1420-6.
  33. Spaeth N, Wyss MT, Pahnke J, Biollaz G, Lutz A, Goepfert K, Westera G, Treyer V, Weber B, Buck A. Uptake of (18)F-fluorocholine, (18)F-fluoro-ethyl-L: -tyrosine and (18)F-fluoro-2-deoxyglucose in F98 gliomas in the rat. Eur J Nucl Med Mol Imaging. 2006;33(6):673-82.
  34. Tipre DN, Zoghbi SS, Liow JS, Green MV, Seidel J, Ichise M, Innis RB, Pike VW. PET Imaging of Brain 5-HT1A Receptors in Rat In Vivo with 18F-FCWAY and Improvement by Successful Inhibition of Radioligand Defluorination with Miconazole. J Nucl Med. 2006;47(2):345-353.
  35. Treyer V, Buck A, Schnider A. Effects of baseline task position on apparent activation in functional imaging of memory. Neuropsychologia. 2006;44(3):462-8.
  36. Van Laere K, Casteels C, De Ceuninck L, Vanbilloen B, Maes A, Mortelmans L, Vandenberghe W, Verbruggen A, Dom R. Dual-Tracer Dopamine Transporter and Perfusion SPECT in Differential Diagnosis of Parkinsonism Using Template-Based Discriminant Analysis. J Nucl Med. 2006;47(3):384-392.
  37. Van Laere K, Nuttin B, Gabriels L, Dupont P, Rasmussen S, Greenberg BD, Cosyns P. Metabolic Imaging of Anterior Capsular Stimulation in Refractory Obsessive-Compulsive Disorder: A Key Role for the Subgenual Anterior Cingulate and Ventral Striatum. J Nucl Med. 2006;47(5):740-747.
  38. von Borczyskowski D, Wilke F, Martin B, Brenner W, Clausen M, Mester J, Buchert R. Evaluation of a new expert system for fully automated detection of the Alzheimer's dementia pattern in FDG PET. Nucl Med Commun. 2006;27(9):739-43.
  39. Wagenknecht G, Belitz H, Wolff R, Castellanos J. Segmentation of ROIs/VOIs from small animal images for functional analysis. Nuclear Instruments and Methods in Physics Research A 569. 2006; 481-487.
  40. Willeit M, Ginovart N, Kapur S, Houle S, Hussey D, Seeman P, Wilson AA. High-Affinity States of Human Brain Dopamine D2/3 Receptors Imaged by the Agonist [(11)C]-(+)-PHNO. Biol Psychiatry. 2006;59(5):389-94.
  41. Zoghbi SS, Shetty HU, Ichise M, Fujita M, Imaizumi M, Liow JS, Shah J, Musachio JL, Pike VW, Innis RB. PET Imaging of the Dopamine Transporter with 18F-FECNT: A Polar Radiometabolite Confounds Brain Radioligand Measurements. J Nucl Med. 2006;47(3):520-7.
2005
  1. Beer AJ, Haubner R, Goebel M, Luderschmidt S, Spilker ME, Wester HJ, Weber WA, Schwaiger M. Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients. J Nucl Med. 2005;46(8):1333-41.
  2. Benveniste H, Fowler JS, Rooney W, Ding Y-S, Baumann AL, Moller DH, Du C, Backus W, Logan J, Carter P, Coplan JD, Biegon A, Rosenblum L, Scharf B, Gatley JS, Volkow ND. (2005) Maternal and Fetal 11C-Cocaine Uptake and Kinetics Measured In Vivo by Combined PET and MRI in Pregnant Nonhuman Primates. J Nucl Med 46:312-320.
  3. Boecker H, Sprenger T, Henriksen G, Toelle TR, Spilker ME. Optimal Duration of PET Studies with 18F-Fluoroethyl-Diprenorphine. J Nucl Med. 2005;46(12):2092-6.
  4. Boumezbeur F, Besret L, Valette J, Gregoire MC, Delzescaux T, Maroy R, Vaufrey F, Gervais P, Hantraye P, Bloch G, Lebon V. Glycolysis versus TCA cycle in the primate brain as measured by combining 18F-FDG PET and 13C-NMR. J Cereb Blood Flow Metab. 2005;25(11):1418-23.
  5. Ciernik IF, Huser M, Burger C, Davis JB, Szekely G. Automated functional image-guided radiation treatment planning for rectal cancer. Int J Radiat Oncol Biol Phys. 2005;62(3):893-900.
  6. Finnema SJ, Seneca N, Farde L, Shchukin E, Sovago J, Gulyas B, Wikstrom HV, Innis RB, Neumeyer JL, Halldin C. A preliminary PET evaluation of the new dopamine D2 receptor agonist [11C]MNPA in cynomolgus monkey. Nucl Med Biol. 2005;32(4):353-60.
  7. Fujita M, Zoghbi SS, Crescenzo MS, Hong J, Musachio JL, Lu J-Q, Liow J-S, Seneca N, Tipre DN, Cropley VL. Quantification of brain phosphodiesterase 4 in rat with (R)-[11C]Rolipram-PET. NeuroImage. 2005;26(4):1201-1210.
  8. Gallezot J-D, Bottlaender M, Gregoire M-C, Roumenov D, Deverre J-R, Coulon C, Ottaviani M, Dolle F, Syrota A, Valette H. (2005) In Vivo Imaging of Human Cerebral Nicotinic Acetylcholine Receptors with 2-18F-Fluoro-A-85380 and PET. J Nucl Med 46:240-247.
  9. Ginovart N, Meyer JH, Boovariwala A, Hussey D, Rabiner EA, Houle S, Wilson AA. Positron emission tomography quantification of [(11)C]-harmine binding to monoamine oxidase-A in the human brain. J Cereb Blood Flow Metab. 2005.
  10. Henze M, Dimitrakopoulou-Strauss A, Milker-Zabel S, Schuhmacher J, Strauss LG, Doll J, Macke HR, Eisenhut M, Debus J, Haberkorn U. Characterization of 68Ga-DOTA-D-Phe1-Tyr3-Octreotide Kinetics in Patients with Meningiomas. J Nucl Med. 2005;46(5):763-9.
  11. Herzog H, Tellmann L, Fulton R, Stangier I, Kops ER, Bente K, Boy C, Hurlemann R, Pietrzyk U. Motion Artifact Reduction on Parametric PET Images of Neuroreceptor Binding. J Nucl Med. 2005;46(6):1059-65.
  12. Jacobs AH, Thomas A, Kracht LW, Li H, Dittmar C, Garlip G, Galldiks N, Klein JC, Sobesky J, Hilker R, Vollmar S, Herholz K, Wienhard K, Heiss WD. 18F-Fluoro-L-Thymidine and 11C-Methylmethionine as Markers of Increased Transport and Proliferation in Brain Tumors. J Nucl Med. 2005;46(12):1948-58.
  13. Kaufmann PA, Namdar M, Matthew F, Roffi M, Aschkenasy SV, van der Loo B, Sutsch G, Luscher TF, Jenni R. Novel doppler assessment of intracoronary volumetric flow reserve: validation against PET in patients with or without flow-dependent vasodilation. J Nucl Med. 2005;46(8):1272-7.
  14. Meyer PT, Elmenhorst D, Zilles K, Bauer A. (2005) Simplified quantification of cerebral A(1) adenosine receptors using [(18)F]CPFPX and PET: Analyses based on venous blood sampling. Synapse 55:212-223.
  15. Muzi M, Vesselle H, Grierson JR, Mankoff DA, Schmidt RA, Peterson L, Wells JM, Krohn KA. (2005) Kinetic Analysis of 3'-Deoxy-3'-Fluorothymidine PET Studies: Validation Studies in Patients with Lung Cancer. J Nucl Med 46:274-282.
  16. Muzi M, Mankoff DA, Grierson JR, Wells JM, Vesselle H, Krohn KA. (2005) Kinetic Modeling of 3'-Deoxy-3'-Fluorothymidine in Somatic Tumors: Mathematical Studies. J Nucl Med 46:371-380.
  17. Praschak-Rieder N, Wilson AA, Hussey D, Carella A, Wei C, Ginovart N, Schwarz MJ, Zach J, Houle S, Meyer JH. Effects of tryptophan depletion on the serotonin transporter in healthy humans. Biol Psychiatry. 2005;58(10):825-30.
  18. Ryzhikov NN, Seneca N, Krasikova RN, Gomzina NA, Shchukin E, Fedorova OS, Vassiliev DA, Gulyas B, Hall H, Savic I, Halldin C. (2005) Preparation of highly specific radioactivity [(18)F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography. Nucl Med Biol 32:109-116.
  19. Schiffer WK, Alexoff DL, Shea C, Logan J, Dewey SL. Development of a simultaneous PET/microdialysis method to identify the optimal dose of (11)C-raclopride for small animal imaging. J Neurosci Methods. 2005;144(1):25-34.
  20. Schmid DT, John H, Zweifel R, Cservenyak T, Westera G, Goerres GW, von Schulthess GK, Hany TF. Fluorocholine PET/CT in patients with prostate cancer: initial experience. Radiology. 2005;235(2):623-8.
  21. Schnider A, Treyer V, Buck A. (2005) The human orbitofrontal cortex monitors outcomes even when no reward is at stake. Neuropsychologia 43:316-323.
  22. Siessmeier T, Zhou Y, Buchholz HG, Landvogt C, Vernaleken I, Piel M, Schirrmacher R, Rosch F, Schreckenberger M, Wong DF, Cumming P, Grunder G, Bartenstein P. Parametric mapping of binding in human brain of d2 receptor ligands of different affinities. J Nucl Med. 2005;46(6):964-72.
  23. Steinert HC, Dellea MM, Burger C, Stahel R. Therapy response evaluation in malignant pleural mesothelioma with integrated PET-CT imaging. Lung Cancer. 2005;49 Suppl 1:S33-5.
  24. Tipre DN, Goldstein DS. Cardiac and extracardiac sympathetic denervation in Parkinson's disease with orthostatic hypotension and in pure autonomic failure. J Nucl Med. 2005;46(11):1775-81.
  25. Vogel R, Indermuhle A, Reinhardt J, Meier P, Siegrist PT, Namdar M, Kaufmann PA, Seiler C. (2005) The quantification of absolute myocardial perfusion in humans by contrast echocardiography: algorithm and validation. J Am Coll Cardiol 45:754-762.
2004
  1. Berding G, Muller-Vahl K, Schneider U, Gielow P, Fitschen J, Stuhrmann M, Harke H, Buchert R, Donnerstag F, Hofmann M, Knoop BO, Brooks DJ, Emrich HM, Knapp WH. (2004) [(123)I]AM281 single-photon emission computed tomography imaging of central cannabinoid CB(1) receptors before and after Delta(9)-tetrahydrocannabinol therapy and whole-body scanning for assessment of radiation dose in tourette patients. Biol Psychiatry 55:904-915
  2. Brenner W, Vernon C, Muzi M, Mankoff DA, Link JM, Conrad EU, Eary JF. (2004) Comparison of different quantitative approaches to 18F-fluoride PET scans. J Nucl Med 45:1493-1500
  3. Fujita M, Varrone A, Kim KM, Watabe H, Zoghbi SS, Seneca N, Tipre D, Seibyl JP, Innis RB, Iida H. (2004) Effect of scatter correction on the compartmental measurement of striatal and extrastriatal dopamine D2 receptors using [123I]epidepride SPET. Eur J Nucl Med Mol Imaging 31:644-654
  4. Ihara M, Tomimoto H, Ishizu K, Mukai T, Yoshida H, Sawamoto N, Inoue M, Doi T, Hashikawa K, Konishi J, Shibasaki H, Fukuyama H. (2004) Decrease in cortical benzodiazepine receptors in symptomatic patients with leukoaraiosis: a positron emission tomography study. Stroke 35:942-947
  5. Itier V, Schonbachler R, Tribollet E, Honer M, Prinz K, Marguerat A, Bertrand S, Bunnelle WH, Schubiger PA, Meyer MD, Sullivan JP, Bertrand D, Westera G. (2004) A-186253, a specific antagonist of the alpha 4 beta 2 nAChRs: its properties and potential to study brain nicotinic acetylcholine receptors. Neuropharmacology 47:538-557
  6. Koepfli P, Wyss CA, Namdar M, Fretz G, Seebauer M, Schirlo C, Kaufmann PA. (2004) Impact of altitude exposure on myocardial blood flow and flow reserve. International Congress Series 1264:111-116
  7. Koepfli P, Wyss CA, Namdar M, Klainguti M, von Schulthess GK, Luscher TF, Kaufmann PA. (2004) {beta}-Adrenergic Blockade and Myocardial Perfusion in Coronary Artery Disease: Differential Effects in Stenotic Versus Remote Myocardial Segments. J Nucl Med 45:1626-1631
  8. Liptrot M, Adams KH, Martiny L, Pinborg LH, Lonsdale MN, Olsen NV, Holm S, Svarer C, Knudsen GM. (2004) Cluster analysis in kinetic modelling of the brain: a noninvasive alternative to arterial sampling. NeuroImage 21:483-493
  9. Meyer PT, Bier D, Holschbach MH, Boy C, Olsson RA, Coenen HH, Zilles K, Bauer A. (2004) Quantification of cerebral A1 adenosine receptors in humans using [18F]CPFPX and PET. J Cereb Blood Flow Metab 24:323-333
  10. Nowak B, Stellbrink C, Sinha AM, Kaiser H-J, Reinartz P, Koos R, Markus K, Hanrath P, Buell U, Schaefer WM. (2004) Effects of cardiac resynchronization therapy on myocardial blood flow measured by oxygen-15 water positron emission tomography in idiopathic-dilated cardiomyopathy and left bundle branch block. The American Journal of Cardiology 93:496-499
  11. Spilker ME, Sprenger T, Valet M, Henriksen G, Wagner K, Wester H-J, Toelle TR, Boecker H. (2004) Quantification of [18F]diprenorphine kinetics in the human brain with compartmental and non-compartmental modeling approaches. NeuroImage 22:1523-1533
  12. Tipre DN, Fujita M, Chin FT, Seneca N, Vines D, Liow JS, Pike VW, Innis RB. (2004) Whole-body biodistribution and radiation dosimetry estimates for the PET dopamine transporter probe 18F-FECNT in non-human primates. Nucl Med Commun 25:737-742
  13. Tipre DN, Lu JQ, Fujita M, Ichise M, Vines D, Innis RB. (2004) Radiation dosimetry estimates for the PET serotonin transporter probe 11C-DASB determined from whole-body imaging in non-human primates. Nucl Med Commun 25:81-86
  14. Weber B, Westera G, Treyer V, Burger C, Khan N, Buck A. (2004) Constant-infusion H(2)15O PET and acetazolamide challenge in the assessment of cerebral perfusion status. J Nucl Med 45:1344-1350
  15. Weber B, Burger C, Wyss MT, von Schulthess GK, Scheffold F, Buck A. (2004) Optical imaging of the spatiotemporal dynamics of cerebral blood flow and oxidative metabolism in the rat barrel cortex. Eur J Neurosci 20:2664-2670
2003
  1. Bauer A, Holschbach MH, Meyer PT, Boy C, Herzog H, Olsson RA, Coenen HH, Zilles K. (2003) In vivo imaging of adenosine A1 receptors in the human brain with [18F]CPFPX and positron emission tomography. NeuroImage 19:1760-1769
  2. Buchert R, Thomasius R, Nebeling B, Petersen K, Obrocki J, Jenicke L, Wilke F, Wartberg L, Zapletalova P, Clausen M. (2003) Long-term effects of "ecstasy" use on serotonin transporters of the brain investigated by PET. J Nucl Med 44:375-384
  3. Buchert R, Wilke F, van den Hoff J, Mester J. (2003) Improved statistical power of the multilinear reference tissue approach to the quantification of neuroreceptor ligand binding by regularization. J Cereb Blood Flow Metab 23:612-620
  4. Ciernik IF, Dizendorf E, Baumert BG, Reiner B, Burger C, Davis JB, Lutolf UM, Steinert HC, Von Schulthess GK. (2003) Radiation treatment planning with an integrated positron emission and computer tomography (PET/CT): a feasibility study. International Journal of Radiation Oncology*Biology*Physics 57:853-863
  5. de Quervain DJ, Henke K, Aerni A, Treyer V, McGaugh JL, Berthold T, Nitsch RM, Buck A, Roozendaal B, Hock C. (2003) Glucocorticoid-induced impairment of declarative memory retrieval is associated with reduced blood flow in the medial temporal lobe. Eur J Neurosci 17:1296-1302
  6. Dizendorf E, Hany TF, Buck A, von Schulthess GK, Burger C. (2003) Cause and magnitude of the error induced by oral CT contrast agent in CT-based attenuation correction of PET emission studies. J Nucl Med 44:732-738
  7. Fujita M, Al-Tikriti MS, Tamagnan G, Zoghbi SS, Bozkurt A, Baldwin RM, Innis RB. (2003) Influence of acetylcholine levels on the binding of a SPECT nicotinic acetylcholine receptor ligand [123I]5-I-A-85380. Synapse 48:116-122
  8. Fujita M, Ichise M, van Dyck CH, Zoghbi SS, Tamagnan G, Mukhin AG, Bozkurt A, Seneca N, Tipre D, DeNucci CC, Iida H, Vaupel DB, Horti AG, Koren AO, Kimes AS, London ED, Seibyl JP, Baldwin RM, Innis RB. (2003) Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET. Eur J Nucl Med Mol Imaging 30:1620-1629
  9. Goerres GW, Burger C, Kamel E, Seifert B, Kaim AH, Buck A, Buehler TC, Von Schulthess GK. (2003) Respiration-induced attenuation artifact at PET/CT: technical considerations. Radiology 226:906-910
  10. Goerres GW, Burger C, Schwitter MR, Heidelberg TN, Seifert B, von Schulthess GK. (2003) PET/CT of the abdomen: optimizing the patient breathing pattern. Eur Radiol 13:734-739
  11. Goerres GW, Ziegler SI, Burger C, Berthold T, Von Schulthess GK, Buck A. (2003) Artifacts at PET and PET/CT caused by metallic hip prosthetic material. Radiology 226:577-584
  12. Henke K, Mondadori CRA, Treyer V, Nitsch RM, Buck A, Hock C. (2003) Nonconscious formation and reactivation of semantic associations by way of the medial temporal lobe. Neuropsychologia 41:863-876
  13. Henke K, Treyer V, Weber B, Nitsch RM, Hock C, Wieser HG, Buck A. (2003) Functional neuroimaging predicts individual memory outcome after amygdalohippocampectomy. Neuroreport 14:1197-1202
  14. Ichise M, Liow JS, Lu JQ, Takano A, Model K, Toyama H, Suhara T, Suzuki K, Innis RB, Carson RE. (2003) Linearized reference tissue parametric imaging methods: application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain. J Cereb Blood Flow Metab 23:1096-1112
  15. Kamel EM, Burger C, Buck A, von Schulthess GK, Goerres GW. (2003) Impact of metallic dental implants on CT-based attenuation correction in a combined PET/CT scanner. Eur Radiol 13:724-728
  16. Quick HH, Kuehl H, Kaiser G, Aker S, Bosk S, Debatin JF, Ladd ME. Interventional MR Angiography with a Floating Table. Radiology. 2003;229(2):598-602
  17. Strauss LG, Dimitrakopoulou-Strauss A, Haberkorn U. (2003) Shortened PET data acquisition protocol for the quantification of 18F-FDG kinetics. J Nucl Med 44:1933-1939
  18. Thireou T, Strauss LG, Dimitrakopoulou-Strauss A, Kontaxakis G, Pavlopoulos S, Santos A. (2003) Performance evaluation of principal component analysis in dynamic FDG-PET studies of recurrent colorectal cancer. Computerized Medical Imaging and Graphics 27:43-51
  19. Treyer V, Jobin M, Burger C, Teneggi V, Buck A. (2003) Quantitative cerebral H2(15)O perfusion PET without arterial blood sampling, a method based on washout rate. Eur J Nucl Med Mol Imaging 30:572-580
  20. Weber B, Spath N, Wyss M, Wild D, Burger C, Stanley R, Buck A. (2003) Quantitative cerebral blood flow measurements in the rat using a beta-probe and H2 15O. J Cereb Blood Flow Metab 23:1455-1460
  21. Wyss CA, Koepfli P, Fretz G, Seebauer M, Schirlo C, Kaufmann PA. (2003) Influence of altitude exposure on coronary flow reserve. Circulation 108:1202-1207
  22. Zimmermann K, Grunberg J, Honer M, Ametamey S, August Schubiger P, Novak-Hofer I. (2003) Targeting of renal carcinoma with 67/64Cu-labeled anti-L1-CAM antibody chCE7: selection of copper ligands and PET imaging. Nuclear Medicine and Biology 30:417-427
2002
  1. Ametamey SM, Bruehlmeier M, Kneifel S, Kokic M, Honer M, Arigoni M, Buck A, Burger C, Samnick S, Quack G, Schubiger PA. (2002) PET studies of 18F-memantine in healthy volunteers. Nuclear Medicine and Biology 29:227-231
  2. Burger C, Goerres G, Schoenes S, Buck A, Lonn AH, Von Schulthess GK. (2002) PET attenuation coefficients from CT images: experimental evaluation of the transformation of CT into PET 511-keV attenuation coefficients. Eur J Nucl Med Mol Imaging 29:922-927
  3. Carroll TJ, Teneggi V, Jobin M, Squassante L, Treyer V, Hany TF, Burger C, Wang L, Bye A, Von Schulthess GK, Buck A. (2002) Absolute quantification of cerebral blood flow with magnetic resonance, reproducibility of the method, and comparison with H2(15)O positron emission tomography. J Cereb Blood Flow Metab 22:1149-1156
  4. Dimitrakopoulou-Strauss A, Strauss LG, Heichel T, Wu H, Burger C, Bernd L, Ewerbeck V. (2002) The role of quantitative (18)F-FDG PET studies for the differentiation of malignant and benign bone lesions. J Nucl Med 43:510-518
  5. Goerres GW, Kamel E, Heidelberg TN, Schwitter MR, Burger C, von Schulthess GK. (2002) PET-CT image co-registration in the thorax: influence of respiration. Eur J Nucl Med Mol Imaging 29:351-360
  6. Goerres GW, Kamel E, Seifert B, Burger C, Buck A, Hany TF, Von Schulthess GK. (2002) Accuracy of image coregistration of pulmonary lesions in patients with non-small cell lung cancer using an integrated PET/CT system. J Nucl Med 43:1469-1475
  7. Ichise M, Toyama H, Innis RB, Carson RE. (2002) Strategies to improve neuroreceptor parameter estimation by linear regression analysis. J Cereb Blood Flow Metab 22:1271-1281
  8. Kamel E, Hany TF, Burger C, Treyer V, Lonn AH, von Schulthess GK, Buck A. (2002) CT vs 68Ge attenuation correction in a combined PET/CT system: evaluation of the effect of lowering the CT tube current. Eur J Nucl Med Mol Imaging 29:346-350
  9. Kamel EM, Goerres GW, Burger C, von Schulthess GK, Steinert HC. (2002) Recurrent laryngeal nerve palsy in patients with lung cancer: detection with PET-CT image fusion -- report of six cases. Radiology 224:153-156
  10. Schonbachler RD, Gucker PM, Arigoni M, Kneifel S, Vollenweider FX, Buck A, Burger C, Berthold T, Bruhlmeier M, Schubiger PA, Ametamey SM. (2002) PET imaging of dopamine transporters in the human brain using [11C]-[beta]-CPPIT, a cocaine derivative lacking the 2[beta]-ester function. Nuclear Medicine and Biology 29:19-27
  11. Tauscher J, Kapur S, Verhoeff NP, Hussey DF, Daskalakis ZJ, Tauscher-Wisniewski S, Wilson AA, Houle S, Kasper S, Zipursky RB. (2002) Brain serotonin 5-HT(1A) receptor binding in schizophrenia measured by positron emission tomography and [11C]WAY-100635. Arch Gen Psychiatry 59:514-520
  12. Verhoeff NP, Hussey D, Lee M, Tauscher J, Papatheodorou G, Wilson AA, Houle S, Kapur S. (2002) Dopamine depletion results in increased neostriatal D(2), but not D(1), receptor binding in humans. Mol Psychiatry 7:233, 322-238
  13. Weber B, Burger C, Biro P, Buck A. (2002) A femoral arteriovenous shunt facilitates arterial whole blood sampling in animals. Eur J Nucl Med Mol Imaging 29:319-323
  14. Weber B, Fouad K, Burger C, Buck A. (2002) White matter glucose metabolism during intracortical electrostimulation: a quantitative [(18)F]Fluorodeoxyglucose autoradiography study in the rat. Neuroimage 16:993-998
2001
  1. Dimitrakopoulou-Strauss A, Strauss LG, Burger C. (2001) Quantitative PET studies in pretreated melanoma patients: a comparison of 6-[18F]fluoro-L-dopa with 18F-FDG and (15)O-water using compartment and noncompartment analysis. J Nucl Med 42:248-256
  2. Dimitrakopoulou-Strauss A, Strauss LG, Schwarzbach M, Burger C, Heichel T, Willeke F, Mechtersheimer G, Lehnert T. (2001) Dynamic PET 18F-FDG studies in patients with primary and recurrent soft-tissue sarcomas: impact on diagnosis and correlation with grading. J Nucl Med 42:713-720
  3. Ginovart N, Wilson AA, Meyer JH, Hussey D, Houle S. (2001) Positron emission tomography quantification of [(11)C]-DASB binding to the human serotonin transporter: modeling strategies. J Cereb Blood Flow Metab 21:1342-1353
  4. Ichise M, Meyer JH, Yonekura Y. (2001) An introduction to PET and SPECT neuroreceptor quantification models. J Nucl Med 42:755-763
  5. Kaim AH, Burger C, Ganter CC, Goerres GW, Kamel E, Weishaupt D, Dizendorf E, Schaffner A, von Schulthess GK. (2001) PET-CT-guided percutaneous puncture of an infected cyst in autosomal dominant polycystic kidney disease: case report. Radiology 221:818-821
  6. Kaufmann PA, Schirlo C, Pavlicek V, Berthold T, Burger C, von Schulthess GK, Koller EA, Buck A. (2001) Increased myocardial blood flow during acute exposure to simulated altitudes. J Nucl Cardiol 8:158-164
  7. Meyer JH, Wilson AA, Ginovart N, Goulding V, Hussey D, Hood K, Houle S. (2001) Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study. Am J Psychiatry 158:1843-1849
  8. Patt JT, Spang JE, Buck A, Cristina H, Arras M, Schubiger PA, Westera G. (2001) Synthesis and in vivo studies of the stereoisomers of N-[11C]methyl-homoepibatidine. Nuclear Medicine and Biology 28:645-655
  9. Wu H, Dimitrakopoulou-Strauss A, Heichel TO, Lehner B, Bernd L, Ewerbeck V, Burger C, Strauss LG. (2001) Quantitative evaluation of skeletal tumours with dynamic FDG PET: SUV in comparison to Patlak analysis. Eur J Nucl Med 28:704-710
2000
  1. Arigoni M, Kneifel S, Fandino J, Khan N, Burger C, Buck A. (2000) Simplified quantitative determination of cerebral perfusion reserve with H2(15)O PET and acetazolamide. Eur J Nucl Med 27:1557-1563
  2. Buck A, Gucker PM, Schonbachler RD, Arigoni M, Kneifel S, Vollenweider FX, Ametamey SM, Burger C. (2000) Evaluation of serotonergic transporters using PET and [11C](+)McN-5652: assessment of methods. J Cereb Blood Flow Metab 20:253-262
  3. Fujita M, Tamagnan G, Zoghbi SS, Al-Tikriti MS, Baldwin RM, Seibyl JP, Innis RB. (2000) Measurement of alpha4beta2 nicotinic acetylcholine receptors with [123I]5-I-A-85380 SPECT. J Nucl Med 41:1552-1560
  4. Schwarzbach MH, Dimitrakopoulou-Strauss A, Willeke F, Hinz U, Strauss LG, Zhang YM, Mechtersheimer G, Attigah N, Lehnert T, Herfarth C. (2000) Clinical value of [18-F]] fluorodeoxyglucose positron emission tomography imaging in soft tissue sarcomas. Ann Surg 231:380-386
1999
  1. Fujita M, Seibyl JP, Verhoeff NP, Ichise M, Baldwin RM, Zoghbi SS, Burger C, Staley JK, Rajeevan N, Charney DS, Innis RB. (1999) Kinetic and equilibrium analyses of [(123)I]epidepride binding to striatal and extrastriatal dopamine D(2) receptors. Synapse 34:290-304
1998
  1. Bicik I, Radanov BP, Schafer N, Dvorak J, Blum B, Weber B, Burger C, von Schulthess GK, Buck A. (1998) PET with 18fluorodeoxyglucose and hexamethylpropylene amine oxime SPECT in late whiplash syndrome. Neurology 51:345-350
  2. Buck A, Schirlo C, Jasinksy V, Weber B, Burger C, von Schulthess GK, Koller EA, Pavlicek V. (1998) Changes of cerebral blood flow during short-term exposure to normobaric hypoxia. J Cereb Blood Flow Metab 18:906-910
  3. Mikolajczyk K, Szabatin M, Rudnicki P, Grodzki M, Burger C. (1998) A JAVA environment for medical image data analysis: initial application for brain PET quantitation. Med Inform (Lond) 23:207-214
1997
  1. Burger C, Buck A. (1997) Requirements and implementation of a flexible kinetic modeling tool. J Nucl Med 38:1818-1823
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