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This tool calculates the grey matter (GM), white matter (WM) and cerebrospinal fluid (CSF) probability maps from a T1-MRI of a human brain. The procedure has three parameters: Sampling distance determines the density of pixels considered in the calculation. Bias Regularisation serves for compensating modulations of the image intensity across the field-of-view. Depending on the degree of the artifact, a corresponding setting can be selected from the list. Cleanup is a procedure for rectifying the segmentation along the boundaries. It is recommended to use the default settings and only experiment with other parameter values if the segmentation fails. The default settings are available by activating the default settings button 
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The results are the three probability maps of GM, WM and CSF which are arranged in this order as the frames in a "dynamic" series.