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Probability Maps Normalization

The probability maps normalization approach is an implementation of the Unified Segmentation procedure in SPM8 developed by Ashburner et al [11]. It is only applicable for stereotactic normalization of T1-MRI brain images to appropriate template images which can be loaded with the button.

Please first load the T1-MRI brain image on the INPUT sub-page and make sure the Species setting is set to HUMAN. Proceed with the probability maps normalization button.

On the REFERENCE sub-page load the reference image either with the shortcut to load an in-built template.

The two relevant templates are the MR (G+W+F Probability) for younger and MR (G+W+F Probability)(Clinical Toolbox) for older subjects.

Probability Maps Normalization Parameters

The normalization algorithm uses several parameters, which are hidden from the user interface. With the button they can be shown and edited.

The parameter details and the deformation method are described in a separate section.

Important: The parameter settings are serialized. The next time Deformable matching is selected for the same species, the last parameter configuration will be applied. This is particularly relevant for the Matching without Interaction functionality.

Starting the Registration

Please use the Normalize button to start the registration of the currently selected INP series to the REF series. In the case of multiple INP series the is also active. It allows matching each INP series to the REF applying the same registration parameters.