Previous Topic

Next Topic

Book Contents

Book Index

Cardiac Flow from Ammonia PET

Three models are available for the quantification of myocardial blood flow from 13NH3 ammonia bolus PET data. Two use the 1-tissue compartment model below, and one the a 2-tissue compartment model with metabolic trapping. The 1-tissue models are preferably used with the first 2-4 minutes of a dynamic measurement, while the 2-tissue model is also adequate for longer durations. This may compensate to some extent the increased vulnerability to identifiability problems due to the higher number of fit parameters in the 2-tissue model.